„The human retinal autofocus“ – Choroidal and scleral thickness changes in response to defocus and elevation of intraocular pressure in myopia

Myopia is a widespread disorder with increasing prevalence. Despite extensive research, its pathogenesis is still poorly understood. It has been shown that the image plane of the retina can be moved forward and backward due to changes in choroidal thickness (CT), e.g. by imposed defocus. Aim of this study is to investigate the effect of imposed myopic defocus and elevation of IOP on CT and scleral thickness (ST) in human myopia using two novel optical coherence tomography (OCT) systems that operate at a longer wavelength (1060nm) compared to commercially available OCTs, allowing quantitative imaging of both CT and ST.